Platycodin D

CAS No. 58479-68-8

Platycodin D ( —— )

Catalog No. M18847 CAS No. 58479-68-8

Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 80 In Stock
25MG 140 In Stock
50MG 214 In Stock
100MG 357 In Stock
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Biological Information

  • Product Name
    Platycodin D
  • Note
    Research use only, not for human use.
  • Brief Description
    Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA).
  • Description
    Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA). Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases, they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    PGE2
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    58479-68-8
  • Formula Weight
    1225.34
  • Molecular Formula
    C57H92O28
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    C1C(CC[C@@]2([C@@H](C[C@@]3([C@@]4(CC[C@H]5C([C@H]([C@H](C[C@@]5(C4CC=C3[C@H]12)C)O)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)(CO)CO)C)C)O)C(=O)O[C@@H]1OC[C@@H]([C@@H]([C@H]1O[C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O[C@@H]1OC[C@H]([C@@H]([C@H]1O)O[C@@H]1OC[C@@]([C@H]1O)(CO)O)O)C)O)O)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kwon OG,ET AL. The Effects of Platycodin D, a Saponin Purified from Platycodi Radix, on Collagen-Induced DBA/1J Mouse Rheumatoid Arthritis. Evid Based Complement Alternat Med. 2014;2014:954508.
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